Ok, so it’s only the audio. This sounds very much like the typical problems some D&R owners see. Just an example: WASAPI problem with D&R Airlite - #12 by Adriaan
It’s not quite clear what is causing them; my impression is that it can vary by mainboard/USB chipset. This is where the hypervisor could play a major role.
Out of curiosity, as you also have Parallels, could you try if it happens there as well? (You can activate a trial license, or we can put another demo into your account, let me now.)